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Mechanical Studies and Thermal Kinetics of Paracetamol Crystals

RAMACHANDRAN ESAKKI, S. Ramukutty

Abstract


Single crystals of paracetamol were crystallized by slow solvent evaporation method. Monoclinic form of the crystal was confirmed using single crystal X-ray diffraction analysis. Microhardness of the crystal was analyzed as a function of the applied load. Kinetic analysis was made from the thermogravimetric analysis/differential thermal analysis (TGA/DTA) data using Coats-Redfern (CR) relation. Thermodynamic parameters were also determined. Arrhenius equation for paracetamol is k = 0.32 × 105 e–89703/RT mol–1s–1.

Keywords: crystals, paracetamol, thermogravimetric

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DOI: https://doi.org/10.37628/ijssm.v2i1.18

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